selected publications
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article
- Crosstalk between cholesterol and PIP2 in the regulation of Kv7. 2/Kv7. 3 channels. Biological Chemistry. :-. 2023-01-01
- Determination of the size of lipid rafts studied through single-molecule FRET simulations. Biophysical Journal. 120:2287-2295. 2021-01-01
- Inhibitory effect of terfenadine on Kir2.1 and Kir2.3 channels. Acta Pharmaceutica. 71:317-324. 2021-01-01
- Kir4.1/kir5.1 channels possess strong intrinsic inward rectification determined by a voltage-dependent k -flux gating mechanism. Journal of General Physiology. 153:-. 2021-01-01
- Riluzole inhibits Kv4.2 channels acting on the closed and closed inactivated states. European Journal of Pharmacology. 899:-. 2021-01-01
- In vitro and in silico characterization of the inhibition of Kir4.1 channels by aminoglycoside antibiotics. British Journal of Pharmacology. 177:4548-4560. 2020-01-01
- Voltage-induced structural modifications on M2 muscarinic receptor and their functional implications when interacting with the superagonist iperoxo. Biochemical Pharmacology. 177:-. 2020-01-01
- Chloroquine inhibits tumor-related Kv10.1 channel and decreases migration of MDA-MB-231 breast cancer cells in vitro. European Journal of Pharmacology. 855:262-266. 2019-01-01
- Cytoskeleton disruption affects Kv2.1 channel function and its modulation by PIP 2. Journal of Physiological Sciences. -. 2019-01-01
- Dual regulation of hEAG1 channels by phosphatidylinositol 4,5-bisphosphate. Biochemical and Biophysical Research Communications. 503:2531-2535. 2018-01-01
- Regulation of Kv2.1 channel inactivation by phosphatidylinositol 4,5-bisphosphate. Scientific Reports. 8:-. 2018-01-01
- Regulation of Kv7.2/Kv7.3 channels by cholesterol: Relevance of an optimum plasma membrane cholesterol content. Biochimica et Biophysica Acta - Biomembranes. 1860:1242-1251. 2018-01-01
- Chloroquine blocks the Kir4.1 channels by an open-pore blocking mechanism. European Journal of Pharmacology. 800:40-47. 2017-01-01
- Extracellular protons enable activation of the calcium-dependent chloride channel TMEM16A. Journal of Physiology. 595:1515-1531. 2017-01-01
- High-potency block of Kir4.1 channels by pentamidine: Molecular basis. European Journal of Pharmacology. 815:56-63. 2017-01-01
- Inhibition of Kir4.1 potassium channels by quinacrine. Brain Research. 1663:87-94. 2017-01-01
- Phytochemicals genistein and capsaicin modulate Kv2.1 channel gating. Pharmacological Reports. 69:1145-1153. 2017-01-01
- Modulation of the voltage-gated potassium channel Kv2.1 by the anti-tumor alkylphospholipid perifosine. Pharmacological Reports. 68:457-461. 2016-01-01
- Revealing the activation pathway for TMEM16A chloride channels from macroscopic currents and kinetic models. Pflugers Archiv European Journal of Physiology. 468:1241-1257. 2016-01-01
- The molecular basis of chloroethylclonidine block of inward rectifier (Kir2.1 and Kir4.1) K channels. Pharmacological Reports. 68:383-389. 2016-01-01
- Inhibition of CaV2.3 channels by NK1 receptors is sensitive to membrane cholesterol but insensitive to caveolin-1. Pflugers Archiv European Journal of Physiology. 467:1699-1709. 2015-01-01
- Modulation of Kv2.1 channels inactivation by curcumin. Pharmacological Reports. 67:1273-1279. 2015-01-01
- Impact of the whole-cell patch-clamp configuration on the pharmacological assessment of the hERG channel: Trazodone as a case example. Journal of Pharmacological and Toxicological Methods. 69:237-244. 2014-01-01
- Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). Journal of Biological Chemistry. 287:40266-40278. 2012-01-01
- Dual regulation of voltage-sensitive ion channels by PIP2. Frontiers in Pharmacology. 03-sep:-. 2012-01-01
- Hypercholesterolemia induces up-regulation of K ACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ. Journal of Biological Chemistry. 287:4925-4935. 2012-01-01
- Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels. Molecular Pharmacology. 82:803-813. 2012-01-01
- PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4–S5 linker. Proceedings of the National Academy of Sciences of the United States of America. 109:E2399-E2408. 2012-01-01
- S( )amphetamine induces a persistent leak in the human dopamine transporter: Molecular stent hypothesis. British Journal of Pharmacology. 165:2749-2757. 2012-01-01
- Mechanisms for Kir channel inhibition by quinacrine: Acute pore block of Kir2.x channels and interference in PIP 2 interaction with Kir2.x and Kir6.2 channels. Pflugers Archiv European Journal of Physiology. 462:505-517. 2011-01-01
- The antimalarial drug mefloquine inhibits cardiac inward rectifier K channels: Evidence for interference in PIP2-channel interaction. Journal of Cardiovascular Pharmacology. 57:407-415. 2011-01-01
- Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism. European Journal of Pharmacology. 638:33-41. 2010-01-01
- Tamoxifen inhibits inward rectifier K 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate- channel interactions. Journal of Pharmacology and Experimental Therapeutics. 331:563-573. 2009-01-01
- A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2. Nature Chemical Biology. 4:624-631. 2008-01-01
- Kv1.5 open channel block by the antiarrhythmic drug disopyramide: Molecular determinants of block. Journal of Pharmacological Sciences. 108:49-55. 2008-01-01
- The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel. Proceedings of the National Academy of Sciences of the United States of America. 105:1364-1368. 2008-01-01
- Block of hERG channels by berberine: Mechanisms of voltage- and state-dependence probed with site-directed mutant channels. Journal of Cardiovascular Pharmacology. 47:21-29. 2006-01-01
- Inhibition of cardiac HERG potassium channels by antidepressant maprotiline. European Journal of Pharmacology. 531:1-8. 2006-01-01
- The D3-dopaminergic agonist 7-hydroxy-dipropylaminotetralin (7-OH-DPAT) increases cardiac action potential duration and blocks human ether-a-go-go-related gene K channel. Journal of Cardiovascular Pharmacology. 47:656-662. 2006-01-01
- Role of rafts in neurological disorders [Participación de rafts en enfermedades neurológicas]. Neurologia. -. 2021-01-01
- Functional marriage in plasma membrane: Critical cholesterol level–optimal protein activity. British Journal of Pharmacology. 2456-2465. 2020-01-01