Document
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Incidence of congenital and postnatal cytomegalovirus infection during the first year of life in Mexican preterm infants
related by: authorship_69165
type: Entity
related by: authorship_69174
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related by: authorship_69168
has funding vehicle: CONACYT‐SALUD‐2015‐1‐261977
type: Information Content Entity
pmid: 35261048
abstract: Cytomegalovirus infection occurs commonly during infancy. Postnatal infection in term infants is usually asymptomatic; however, infection in preterm infants can be associated with clinical manifestations during the neonatal period. Nevertheless, few studies to assess the frequency of cytomegalovirus infection in preterm infants have been performed outside of high-income countries. We analyzed the incidence of congenital and postnatal cytomegalovirus infection in a cohort of preterm infants. Cytomegalovirus infection was detected during the neonatal period in four of 178 infants; in three of them, the virus was detected during the first 3 weeks of life and, therefore, congenital infection was confirmed (1.7%25 incidence). Postnatal infection was detected in 44 (36.4%25) of 121 infants who were assessed after discharge from the neonatal intensive care unit. Cytomegalovirus infection was significantly associated with the duration of breastfeeding. In addition, we characterized cytomegalovirus strains detected in infants together with sequences available at GenBank, based on sequences of the UL18 gene. Cytomegalovirus UL18-sequences clustered in five distinct clades (A–E), and sequences obtained from infants in our study were distributed in four of the five clades; 44.4%25 of these sequences were included in clade E. Breastfeeding duration was shorter on average (5.6 months) in infants with sequences in clade E compared to infants with sequences in the other three clades (8.2 months; p =.07). In conclusion, we provide information regarding the high incidence of cytomegalovirus infection in preterm infants. Further studies are warranted to assess if cytomegalovirus strain characteristics are associated with the risk of infection acquisition during infancy. © 2022 Wiley Periodicals LLC.
date time value: article date 9991
most specific type: Article
related by: authorship_69167
type: Document
freetext keyword: breast milk; congenital infection; cytomegalovirus; herpesvirus; postnatal infection Article; breast feeding; congenital infection; cytomegalovirus infection; Herpesviridae; hospitalization; human; infant; lung dysplasia; neonatal intensive care unit; newborn; newborn period; newborn sepsis; polymerase chain reaction; prematurity; respiratory distress syndrome; breast milk; Cytomegalovirus; female; genetics; incidence; Breast Feeding; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incidence; Infant; Infant, Newborn; Infant, Premature; Milk, Human
e iscopus: 2-s2.0-85126386819
related by: authorship_69169
crisid: 9991
most specific type: Document
related by: authorship_69170
related by: authorship_69173
related by: authorship_69172
type: Thing
estado: published
origen: scopus
type: Continuant
related by: authorship_69164
type: Article
volume: 94
has publication venue: Journal of Medical Virology
page end: 3358
page start: 3349
doi: 10.1002/jmv.27705
type: Generically Dependent Continuant
issue: 7

Continuant
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Entity
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CONACYT‐SALUD‐2015‐1‐261977
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type: BFO_0000020
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type: Continuant
funding vehicle for: Incidence of congenital and postnatal cytomegalovirus infection during the first year of life in Mexican preterm infants

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RDF description of Incidence of congenital and postnatal cytomegalovirus infection during the first year of life in Mexican preterm infants - http://orbis.uaslp.mx/vivo/individual/scopus9990
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date: 2026-08-24T21:51:07
publisher: vivo
type: Document

Article
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Information Content Entity
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Journal of Medical Virology
type: Periodical
type: Collection
type: Journal
type: Document
publication venue for: Incidence of congenital and postnatal cytomegalovirus infection during the first year of life in Mexican preterm infants
type: Generically Dependent Continuant
type: Information Content Entity
type: Continuant
type: Thing
type: Entity