Seed-based expression strategies
most specific type: Chapter
type: Book Section
e iscopus: 2-s2.0-84929870155
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page end: 93
estado: published
abstract: Among the current molecular pharming approaches, seed-based expression offers particular advantages as heterologous proteins can be produced at high levels in a highly stable biomass that can also serve as an oral vaccine after either minimal or no processing. Therefore, seeds can be readily used as platforms for the production of low-cost vaccines that are environmentally friendly and easy to administer. In this chapter, various strategies that address expression of immunogens in seeds are presented. Seed-based approaches that have been undertaken to develop candidate vaccines against cholera, malaria, hepatitis B, and diarrhea are featured as examples of the promising potential of these approaches. Moreover, insights into the immunogenic properties of seed-based candidate vaccines are explored. In addition, efforts that prevent undesirable gene flow and release of transgene(s) into the environment are also explored. © 2014 Springer Science Business Media New York. All rights reserved.
doi: 10.1007/978-1-4939-0850-9_5
type: Document Part
type: Entity
has publication venue: Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View
type: Document
page start: 79
type: Thing
related by: authorship_46681
abstract: Among the current molecular pharming approaches, seed-based expression offers particular advantages as heterologous proteins can be produced at high levels in a highly stable biomass that can also serve as an oral vaccine after either minimal or no processing. Therefore, seeds can be readily used as platforms for the production of low-cost vaccines that are environmentally friendly and easy to administer. In this chapter, various strategies that address expression of immunogens in seeds are presented. Seed-based approaches that have been undertaken to develop candidate vaccines against cholera, malaria, hepatitis B, and diarrhea are featured as examples of the promising potential of these approaches. Moreover, insights into the immunogenic properties of seed-based candidate vaccines are explored. In addition, efforts that prevent undesirable gene flow and release of transgene(s) into the environment are also explored. © 2014 Springer Science%2bBusiness Media New York. All rights reserved.
date time value: chapter date 7275
type: Chapter
most specific type: Document
type: Information Content Entity
freetext keyword: Biopharmaceuticals; Immune responses; Molecular pharming; Seed-based candidate vaccine; Transgenic seed
crisid: 7275
type: Generically Dependent Continuant
related by: authorship_46682
origen: scopus
related by: authorship_46683

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View
type: Generically Dependent Continuant
type: Document
type: Book
type: Information Content Entity
type: Entity
publication venue for: Seed-based expression strategies
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Continuant
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Book Section
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RDF description of Seed-based expression strategies - http://orbis.uaslp.mx/vivo/individual/scopus7274
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date: 2026-08-28T02:53:58
publisher: vivo
type: Document

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Chapter
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