Central nervous system disorders in infants with congenital cytomegalovirus infection
issue: 3
manufactures: Hoffmann La Roche, Mexico
freetext keyword: Cytomegalovirus; Cytomegalovirus infections; Hearing loss; Neurological disorders ganciclovir; valganciclovir; antiviral therapy; autocrine effect; calcium cell level; central nervous system disease; clinical feature; Cytomegalovirus; cytomegalovirus infection; disease predisposition; hearing impairment; human; incidence; infection rate; mental deficiency; nerve degeneration; neuroimaging; neurologic disease; neuropathology; nonhuman; nuclear magnetic resonance imaging; paracrine signaling; perception deafness; polymerase chain reaction; pregnant woman; review; seroepidemiology; South and Central America; virus culture; virus detection; virus isolation; virus reactivation; virus replication; virus titration; virus transmission; Animals; Central Nervous System Diseases; Central Nervous System Infections; Cytomegalovirus Infections; Hearing Loss; Humans; Incidence; Infant; Infant, Newborn; Latin America; Mice
type: Document
crisid: 6990
type: Thing
volume: 32
related by: authorship_45455
type: Entity
type: Review
page end: 284
related by: authorship_45457
type: Generically Dependent Continuant
type: Information Content Entity
pmid: 20406606
origen: scopus
page start: 278
date time value: review date 6990
type: Continuant
abstract: Background: Congenital cytomegalovirus is the most common cause of congenital infection in developed countries and a major etiology for neurological disability in children. In many countries, there is low awareness of the importance of this virus as a cause of neurological disorders. Methods: We reviewed current knowledge regarding neurological disorders associated to congenital cytomegalovirus infection and analysed the epidemiology of this infection in Latin American countries. Results: The incidence of congenital cytomegalovirus infection reported from Latin American countries ranges from 0 to 6.8%25 in different settings. Congenital cytomegalovirus infection is a common cause of hearing deficits and mental impairment in children. However, the impact of this infection as a cause of neurological disorders in Latin American countries remains poorly documented. Discussion: Actions are needed to increase knowledge regarding the frequency and impact of congenital cytomegalovirus infection on Latin American children, as well as to increase awareness of the general population and the medical community regarding the need to identify infants infected in utero by this virus and to carefully evaluate their neurological development throughout childhood. © 2010 W. S. Maney %26 Son Ltd.
type: Article
chemicalscas: ganciclovir, 82410-32-0; valganciclovir, 175865-59-5, 175865-60-8, 175865-61-9, 175865-62-0, 175865-64-2, 175865-67-5
doi: 10.1179/016164110X12645013284293
most specific type: Document
estado: published
tradenames: cymevene, Hoffmann La Roche, Mexico; valcyte, Hoffmann La Roche
related by: authorship_45456
most specific type: Review
has publication venue: Neurological Research
e iscopus: 2-s2.0-77951221283

Document
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Neurological Research
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publication venue for: Central nervous system disorders in infants with congenital cytomegalovirus infection
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type: Entity
type: Journal
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Continuant
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Entity
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Review
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Generically Dependent Continuant
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RDF description of Central nervous system disorders in infants with congenital cytomegalovirus infection - http://orbis.uaslp.mx/vivo/individual/scopus6989
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date: 2026-08-24T21:50:58
publisher: vivo
type: Document

Article
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