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RDF description of Point-of-care detection of neutrophils in live skin microsamples using chemiluminescence - http://orbis.uaslp.mx/vivo/individual/scopus6393
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date: 2026-08-25T05:41:09
publisher: vivo
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Article
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493249/279909
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funding vehicle for: Point-of-care detection of neutrophils in live skin microsamples using chemiluminescence

Point-of-care detection of neutrophils in live skin microsamples using chemiluminescence
artnum: e201960170
type: Article
date time value: article date 6394
type: Continuant
type: Information Content Entity
origen: scopus
freetext keyword: chemiluminescence; infection; inflammation; neutrophil; skin Diagnosis; Mammals; Pathology; Skin; Clinical investigation; infection; inflammation; Minimally invasive; neutrophil; Point of care; Point of care diagnostic; Small footprints; Chemiluminescence
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type: Document
most specific type: Article
related by: authorship_41582
issue: 5
type: Generically Dependent Continuant
pmid: 32048794
has funding vehicle: 493249/279909
doi: 10.1002/jbio.201960170
volume: 13
has publication venue: Journal of Biophotonics
related by: authorship_41580
crisid: 6394
estado: published
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e iscopus: 2-s2.0-85083814199
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abstract: Many skin diseases are defined by the presence of neutrophils, which are among the first cells to respond to infection and inflammation. Currently, neutrophil identification in the skin is costly and slow. The objectives of the present work are to investigate the feasibility of detecting the presence of neutrophils in live skin microsamples using chemiluminescence and develop a device and procedures that will enable preclinical and clinical investigations. Our approach consists of collecting skin microsamples and exposing them to reagents that activate neutrophils and amplify the light emission produced by chemiluminescence. Experiments using live pig skin with and without inflammation show that it is feasible to detect the presence of neutrophils in the skin. The proposed method is minimally invasive, simple, fast, and does not require user specialization. The developed system is compact in size with a small footprint, which makes it portable and suitable for point-of-care diagnostics. © 2020 WILEY-VCH Verlag GmbH %26 Co. KGaA, Weinheim
related by: authorship_41579
most specific type: Document

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Journal of Biophotonics
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publication venue for: Point-of-care detection of neutrophils in live skin microsamples using chemiluminescence
type: Periodical
type: Document
type: Information Content Entity
type: Journal
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type: Continuant