Document
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individual
rights: termsOfUse
date: 2026-08-26T10:46:16
publisher: vivo
type: Document
label: RDF description of Identification of profiles of volatile organic compounds in exhaled breath by means of an electronic nose as a proposal for a screening method for breast cancer: A case-control study - http://orbis.uaslp.mx/vivo/individual/scopus6383

Article
type: Class

Identification of profiles of volatile organic compounds in exhaled breath by means of an electronic nose as a proposal for a screening method for breast cancer: A case-control study
related by: authorship_41515
doi: 10.1088/1752-7163/aba83f
type: Document
accesstype: All Open Access, Hybrid Gold
tradenames: Cyranose 320
related by: authorship_41511
date time value: article date 6384
freetext keyword: Breast cancer; Breath analysis; Electronic nose; Multivariate analysis; Screening volatile organic compound; volatile organic compound; adult; Article; breast biopsy; breast cancer; breast imaging reporting and data system; breathing; cancer patient; cancer screening; case control study; clinical practice; controlled study; cross-sectional study; echomammography; expired air; female; human; human tissue; major clinical study; mammography; middle aged; observational study; pilot study; predictive value; priority journal; prospective study; sensitivity and specificity; support vector machine; breast tumor; breath analysis; discriminant analysis; electronic nose; exhalation; principal component analysis; procedures; receiver operating characteristic; reproducibility; Adult; Breast Neoplasms; Breath Tests; Case-Control Studies; Cross-Sectional Studies; Discriminant Analysis; Electronic Nose; Exhalation; Female; Humans; Middle Aged; Principal Component Analysis; Reproducibility of Results; ROC Curve; Volatile Organic Compounds
e iscopus: 2-s2.0-85092680554
type: Generically Dependent Continuant
related by: authorship_41508
abstract: The objective of the present study was to identify volatile prints from exhaled breath, termed breath-print, from breast cancer (BC) patients and healthy women by means of an electronic nose and to evaluate its potential use as a screening method. A cross-sectional study was performed on 443 exhaled breath samples from women, of whom 262 had been diagnosed with BC by biopsy and 181 were healthy women (control group). Breath-print analysis was performed utilizing the Cyranose 320 electronic nose. Group data were evaluated by principal component analysis (PCA), canonical discriminant analysis (CDA), and support vector machine (SVM), and the test%27s diagnostic power was evaluated by means of receiver operating characteristic (ROC) curves. The results obtained using the model generated from the CDA, which best describes the behavior of the assessed groups, indicated that the breath-print of BC patients was different from that of healthy women and that they presented with a variability of up to 98.8%25 and a correct classification of 98%25. The sensitivity, specificity, negative predictive value, and positive predictive value reached 100%25 according to the ROC curve. The present study demonstrates the capability of the electronic nose to separate between healthy subjects and BC patients. This research could have a beneficial impact on clinical practice as we consider that this test could probably be used at the first point before the application of established gold tests (mammography, ultrasound, and biopsy) and substantially improve screening tests in the general population. © 2020 The Author(s).
pmid: 32698165
origen: scopus
related by: authorship_41516
artnum: 46009
crisid: 6384
related by: authorship_41510
related by: authorship_41512
issue: 4
related by: authorship_41513
most specific type: Document
type: Continuant
most specific type: Article
related by: authorship_41509
type: Article
related by: authorship_41517
chemicalscas: Volatile Organic Compounds
type: Information Content Entity
estado: published
abstract: The objective of the present study was to identify volatile prints from exhaled breath, termed breath-print, from breast cancer (BC) patients and healthy women by means of an electronic nose and to evaluate its potential use as a screening method. A cross-sectional study was performed on 443 exhaled breath samples from women, of whom 262 had been diagnosed with BC by biopsy and 181 were healthy women (control group). Breath-print analysis was performed utilizing the Cyranose 320 electronic nose. Group data were evaluated by principal component analysis (PCA), canonical discriminant analysis (CDA), and support vector machine (SVM), and the test's diagnostic power was evaluated by means of receiver operating characteristic (ROC) curves. The results obtained using the model generated from the CDA, which best describes the behavior of the assessed groups, indicated that the breath-print of BC patients was different from that of healthy women and that they presented with a variability of up to 98.8%25 and a correct classification of 98%25. The sensitivity, specificity, negative predictive value, and positive predictive value reached 100%25 according to the ROC curve. The present study demonstrates the capability of the electronic nose to separate between healthy subjects and BC patients. This research could have a beneficial impact on clinical practice as we consider that this test could probably be used at the first point before the application of established gold tests (mammography, ultrasound, and biopsy) and substantially improve screening tests in the general population. © 2020 The Author(s).
volume: 14
has publication venue: Journal of Breath Research
type: Thing
related by: authorship_41514
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Information Content Entity
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Journal of Breath Research
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publication venue for: Identification of profiles of volatile organic compounds in exhaled breath by means of an electronic nose as a proposal for a screening method for breast cancer: A case-control study
type: Continuant