Document
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Health and Technology
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publication venue for: Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy
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Continuant
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C18-FAI-05-53.53
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funding vehicle for: Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy

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SEP CB2017 - A1-S-45611
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type: BFO_0000020
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funding vehicle for: Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy

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RDF description of Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy - http://orbis.uaslp.mx/vivo/individual/scopus6284
rights: termsOfUse
date: 2026-08-24T21:51:24
publisher: vivo
type: Document

Article
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Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy
related by: authorship_40954
related by: authorship_40951
abstract: Parkinson’s disease is a neurodegenerative pathology difficult to diagnose. Researches have confirmed the presences of death cells in the brain produced by the modification of a protein called alpha-synuclein synuclein in people with Parkinson disease. Currently, a great amount of research is conducted to identify its biomarkers for early diagnostics. Recently, a studio found differences between the alpha- synuclein of the skin from Parkinson’s disease and normal patients. In this paper, we use Raman spectroscopy through a numerical model to simulate the vibrational modes of well-defined finite clusters of alpha-synuclein in normal and pathological state, using the Gaussian09 software. The results of the model in the range of x − y cm−1 are in good agreement with the experimental Raman spectra acquired from human skin with alpha-synuclein in the normal and pathological state. © 2019, IUPESM and Springer-Verlag GmbH Germany, part of Springer Nature.
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has publication venue: Health and Technology
has funding vehicle: Consejo Nacional de Ciencia y Tecnología, CONACYT
page end: 470
origen: scopus
issue: 2
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date time value: article date 6285
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has funding vehicle: SEP CB2017 - A1-S-45611
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e iscopus: 2-s2.0-85073946098
volume: 10
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freetext keyword: Alpha-synuclein; Density Functional theory; Parkinson’s disease; Raman spectroscopy alpha synuclein; Article; conformational transition; density functional theory; human; kernel method; molecular model; neuropathology; Parkinson disease; Raman spectrometry; theoretical model; vibrational spectroscopy
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most specific type: Article
estado: published
related by: authorship_40950
chemicalscas: alpha synuclein, 154040-18-3
page start: 465
doi: 10.1007/s12553-019-00367-8
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crisid: 6285

Consejo Nacional de Ciencia y Tecnología, CONACYT
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funding vehicle for: Analysis of vibrational modes from alpha-synuclein: a theoretical model using density functional theory and Raman spectroscopy

Information Content Entity
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