Document
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Pharmacy and Pharmacology Communications
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type: Journal
type: Collection
type: Generically Dependent Continuant
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publication venue for: Evidence Against the Involvement of Nutritional Habits in the Inter‐ethnic Variability with Regard to Oral Nifedipine Bioavailability
type: Thing
type: Continuant
type: Information Content Entity
type: Periodical

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Evidence Against the Involvement of Nutritional Habits in the Inter‐ethnic Variability with Regard to Oral Nifedipine Bioavailability
type: Generically Dependent Continuant
type: Document
volume: 1
crisid: 456
page start: 495
most specific type: Article
type: Thing
estado: published
related by: authorship 2029
related by: authorship 2028
origen: scopus
related by: authorship 2031
related by: authorship 2027
issue: 10
related by: authorship 2030
related by: authorship 2026
abstract: In order to study if nutritional habits are involved in inter‐ethnic differences in nifedipine pharmacokinetics, the bioavailability of a single oral dose of 10 mg nifedipine was studied in ten Mexican healthy volunteers maintained on a typical Mexican corn‐rich diet and on a Western corn‐free diet according to a randomized cross‐over design. AUC0–12 was 283 ± 31 and 327 ± 32 ng h mL−1 whereas Cmax was 107 ± 12 and 134 ± 11 ng mL−1 for the corn‐rich and corn‐free diets, respectively. There were no significant differences between diets in these parameters. AUC and Cmax values observed in Mexicans with both diets were higher than those reported for Caucasian populations. The results confirm the presence of an inter‐ethnic variability with regard to nifedipine pharmacokinetics. These differences, however, do not appear to be due to nutritional habits. 1995 Royal Pharmaceutical Society of Great Britain
type: Information Content Entity
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e iscopus: 2-s2.0-84988183471
type: Article
has publication venue: Pharmacy and Pharmacology Communications
doi: 10.1111/j.2042-7158.1995.tb00363.x
page end: 497
date time value: article date 456
type: Continuant
most specific type: Document

Generically Dependent Continuant
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individual
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date: 2026-08-25T22:11:53
publisher: vivo
type: Document
label: RDF description of Evidence Against the Involvement of Nutritional Habits in the Inter‐ethnic Variability with Regard to Oral Nifedipine Bioavailability - http://orbis.uaslp.mx/vivo/individual/scopus455

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