Journal of Rheumatology
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publication venue for: Factors associated with mortality and infections in patients with systemic lupus erythematosus with diffuse alveolar hemorrhage
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RDF description of Factors associated with mortality and infections in patients with systemic lupus erythematosus with diffuse alveolar hemorrhage - http://orbis.uaslp.mx/vivo/individual/scopus3867
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date: 2026-08-24T21:51:11
publisher: vivo
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Factors associated with mortality and infections in patients with systemic lupus erythematosus with diffuse alveolar hemorrhage
related by: authorship_22303
type: Continuant
related by: authorship_22302
related by: authorship_22315
related by: authorship_22316
type: Article
freetext keyword: Diffuse alveolar hemorrhage; Infections; Mortality; Systemic lupus erythematosus C reactive protein; C reactive protein; adult; adult disease; APACHE; article; artificial ventilation; bacterial infection; child; childhood disease; clinical article; clinical feature; controlled study; diffuse alveolar hemorrhage; disease association; female; human; hypocomplementemia; kidney failure; lung hemorrhage; male; medical record review; mortality; priority journal; recurrent disease; systemic lupus erythematosus; systemic mycosis; thrombocytopenia; adolescent; age; clinical trial; comorbidity; comparative study; complication; Hemorrhage; infection; lung alveolus; Lung Diseases; Lupus Erythematosus, Systemic; metabolism; multicenter study; register; retrospective study; risk factor; sex difference; survival rate; Adolescent; Adult; Age Factors; C-Reactive Protein; Child; Comorbidity; Female; Hemorrhage; Humans; Infection; Lung Diseases; Lupus Erythematosus, Systemic; Male; Pulmonary Alveoli; Registries; Renal Insufficiency; Respiration, Artificial; Retrospective Studies; Risk Factors; Sex Factors; Survival Rate; Thrombocytopenia
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chemicalscas: C reactive protein, 9007-41-4; C-Reactive Protein
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has publication venue: Journal of Rheumatology
related by: authorship_22305
related by: authorship_22304
date time value: article date 3868
abstract: Objective: To evaluate factors associated with mortality and infections in patients with systemic lupus erythematosus (SLE) and diffuse alveolar hemorrhage (DAH). Methods: A retrospective chart review was carried out for medical admissions of patients with a diagnosis of SLE and DAH in 9 hospitals. Clinical and laboratory data were recorded for each patient at DAH diagnosis. Results: We included 57 episodes of DAH of 50 patients (7 recurrences), 49 women (86%25), 14 juvenile SLE (24.6%25); 24 had died (42.1%25). In the chart review we detected infection in 22 episodes (38.6%25): 8 invasive fungal infections, 16 bacterial infections, and 2 patients had both types. In the bivariate analysis, factors associated with mortality were high Acute Physiology and Chronic Health Evaluation II scores, requirement of mechanical ventilation (OR 15.0, 95%25 CI 1.9 to 662.2), infections (fungal or bacterial; OR 3.2, CI 0.9 to 11.1), renal failure (OR 4.9, CI 1.4 to 18.0), and thrombocytopenia (OR 4.3, CI 1.2 to 15.6). We found similar mortality between children and adults. Infections were associated with treatment for SLE, requirement of mechanical ventilation, hypocomplementemia, and high levels of C-reactive protein. Conclusion: Infection is a frequent finding in patients with DAH and SLE; we found similar mortality between adult SLE and juvenile SLE. Factors that we describe associated with infections may influence the therapeutic selection for these patients. Copyright © 2014. All rights reserved.
related by: authorship_22317
doi: 10.3899/jrheum.130927
related by: authorship_22318
most specific type: Document
crisid: 3868
estado: published
pmid: 24986849
issue: 8
related by: authorship_22301
related by: authorship_22309
volume: 41
related by: authorship_22308
related by: authorship_22313
related by: authorship_22314
type: Generically Dependent Continuant
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origen: scopus
page end: 1661
e iscopus: 2-s2.0-84905472301
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page start: 1656
related by: authorship_22310

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