Document
type: Class

Continuant
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Acute effects of autoadjusting and fixed continuous positive airway pressure treatments on cardiorespiratory coupling in obese patients with obstructive sleep apnea
volume: 25
type: Continuant
type: Article
type: Entity
type: Document
estado: published
issue: 2
most specific type: Article
type: Generically Dependent Continuant
related by: authorship_21417
abstract: Background Treatment with positive airway pressure devices improved signs and symptoms of obstructive sleep apnea syndrome (OSA); however, auto-adjusting positive pressure (APAP) device was not as effective as continuous positive airway pressure (CPAP) in reducing arterial blood pressure and insulin resistance. The role played by autonomic cardiac regulation remains to be clarified. We aimed to test the effects of CPAP and APAP on autonomic regulation and cardiorespiratory coupling during sleep. Methods We retrospectively analyzed full-night polysomnographic studies. 19 patients newly diagnosed with severe OSA (AHI > 30) and 7 obese subjects without OSA (CON) were enrolled. Each OSA subject was assigned to CPAP or APAP treatment and underwent a sleep study after 1 week of treatment. Spectral and cross-spectral analyses of heart rate variability (HRV) and respiration were performed to assess autonomic profile and coherence (K2) between respiration and HF oscillation during sleep in CPAP, APAP and CON groups. Results In CPAP and CON, LFnu and LF/HF, markers of sympathetic modulation, decreased from N2 to N3 and increased during REM sleep (p < 0.001), while in APAP group, sympathetic modulation was significantly higher compared with those of CPAP and CON during all sleep stages. K2 values were lower in APAP compared with those in CPAP and CON. Conclusion APAP treatment was characterized by a greater sympathetic activation and it was associated with a lower cardio-respiratory coupling compared with CPAP. This might account for the different effects on cardiovascular risk factors induced by the two treatments. © 2013 European Federation of Internal Medicine.
e iscopus: 2-s2.0-84894076347
page end: 168
pmid: 24373628
has publication venue: European Journal of Internal Medicine
origen: scopus
doi: 10.1016/j.ejim.2013.11.009
related by: authorship_21416
crisid: 3725
page start: 164
related by: authorship_21421
related by: authorship_21418
type: Thing
most specific type: Document
related by: authorship_21420
type: Information Content Entity
date time value: article date 3725
freetext keyword: Autonomic nervous system; Continuous positive airway pressure; Heart rate variability; Obstructive sleep apnea; Sleep; Sympathovagal balance Autonomic nervous system; Continuous positive airway pressure; Heart rate variability; Obstructive sleep apnea; Sleep; Sympathovagal balance; Adult; Autonomic Nervous System; Case-Control Studies; Cohort Studies; Continuous Positive Airway Pressure; Female; Heart Rate; Humans; Male; Middle Aged; Obesity; Polysomnography; Positive-Pressure Respiration; Respiration; Retrospective Studies; Sleep Apnea, Obstructive
related by: authorship_21422
related by: authorship_21419

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individual
rights: termsOfUse
date: 2026-08-27T05:46:30
publisher: vivo
type: Document
label: RDF description of Acute effects of autoadjusting and fixed continuous positive airway pressure treatments on cardiorespiratory coupling in obese patients with obstructive sleep apnea - http://orbis.uaslp.mx/vivo/individual/scopus3724

Article
type: Class

European Journal of Internal Medicine
type: Continuant
type: Collection
type: Periodical
publication venue for: Acute effects of autoadjusting and fixed continuous positive airway pressure treatments on cardiorespiratory coupling in obese patients with obstructive sleep apnea
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type: Document
type: Thing
type: Journal
type: Information Content Entity
type: Generically Dependent Continuant

Information Content Entity
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