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Universitat Politècnica de València, UPV
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funding vehicle for: Electrical-thermal performance of a cooled RF applicator for hepatic ablation with additional distant infusion of hypertonic saline: In vivo study and preliminary computer modeling

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date: 2026-08-27T12:49:45
publisher: vivo
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label: RDF description of Electrical-thermal performance of a cooled RF applicator for hepatic ablation with additional distant infusion of hypertonic saline: In vivo study and preliminary computer modeling - http://orbis.uaslp.mx/vivo/individual/scopus3130

Article
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Ministerio de Ciencia e Innovación, MICINN: TEC2008-01369/TEC, TEC2011-27133-C02-01
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funding vehicle for: Electrical-thermal performance of a cooled RF applicator for hepatic ablation with additional distant infusion of hypertonic saline: In vivo study and preliminary computer modeling

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International Journal of Hyperthermia
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publication venue for: Electrical-thermal performance of a cooled RF applicator for hepatic ablation with additional distant infusion of hypertonic saline: In vivo study and preliminary computer modeling

Electrical-thermal performance of a cooled RF applicator for hepatic ablation with additional distant infusion of hypertonic saline: In vivo study and preliminary computer modeling
has funding vehicle: Universitat Politècnica de València, UPV
doi: 10.3109/02656736.2012.711894
tradenames: Cool-tip electrode, Valleylab, United States
e iscopus: 2-s2.0-84867570591
abstract: Purpose: The Cool-tip electrode is one of the most widely employed applicators in radiofrequency (RF) hepatic ablation. Previous research demonstrated that it is possible to enlarge coagulation volume when the single cooled electrode is associated with distant infusion of saline (hybrid applicator). The aim of this study was to compare the electrical-thermal behaviour of the Cool-tip electrode with that of the hybrid applicator. Materials and methods: Forty-two RF ablations were performed on a total of 10 pigs: 22 with the Cool-tip electrode and 20 with the hybrid applicator (low infused saline volumetric flow rate of 6mL/h at 2mm distance). We compared both electrical performance (delivered power and number of roll-offs, i.e. sudden rises in impedance that interrupt the power delivery) and coagulation zone characteristics. In addition, we built a one-dimensional model to provide a basic physical explanation of the difference in performance between the different applicators. Results: The experimental results showed that the number of roll-offs with the Cool-tip electrode was higher (24.3±3.1 versus 6.7±7.0). The hybrid applicator created larger coagulation volumes (19.7±9.5 cm versus 9.5±5.8 cm) with larger transverse diameters (2.5±0.6 versus 1.9±0.5cm). The one-dimensional model confirmed the delay in the incidence of the first roll-off, but not the heterogeneity of the hybrid applicator%27s electrical performance in the experiments. Conclusions: The hybrid applicator produces fewer roll-off episodes than the Cool-tip electrode and creates larger coagulation volumes with larger transverse diameters. © 2012 Informa UK Ltd All rights reserved.
freetext keyword: Computer modelling; Cool-tip electrode; Hepatic ablation; Radiofrequency ablation; Saline infusion; Tumour ablation sodium chloride; animal experiment; animal tissue; article; computer model; cool tip electrode; electrical parameters; flow rate; hybrid applicator; impedance; in vivo study; liver; nonhuman; radiation applicator; radiofrequency ablation; swine; thermal analysis; Animals; Computer Simulation; Electrocoagulation; Electrodes; Infusions, Intralesional; Liver; Models, Theoretical; Saline Solution, Hypertonic; Swine; Temperature
crisid: 3131
volume: 28
abstract: Purpose: The Cool-tip electrode is one of the most widely employed applicators in radiofrequency (RF) hepatic ablation. Previous research demonstrated that it is possible to enlarge coagulation volume when the single cooled electrode is associated with distant infusion of saline (hybrid applicator). The aim of this study was to compare the electrical-thermal behaviour of the Cool-tip electrode with that of the hybrid applicator. Materials and methods: Forty-two RF ablations were performed on a total of 10 pigs: 22 with the Cool-tip electrode and 20 with the hybrid applicator (low infused saline volumetric flow rate of 6mL/h at 2mm distance). We compared both electrical performance (delivered power and number of roll-offs, i.e. sudden rises in impedance that interrupt the power delivery) and coagulation zone characteristics. In addition, we built a one-dimensional model to provide a basic physical explanation of the difference in performance between the different applicators. Results: The experimental results showed that the number of roll-offs with the Cool-tip electrode was higher (24.3±3.1 versus 6.7±7.0). The hybrid applicator created larger coagulation volumes (19.7±9.5 cm versus 9.5±5.8 cm) with larger transverse diameters (2.5±0.6 versus 1.9±0.5cm). The one-dimensional model confirmed the delay in the incidence of the first roll-off, but not the heterogeneity of the hybrid applicator's electrical performance in the experiments. Conclusions: The hybrid applicator produces fewer roll-off episodes than the Cool-tip electrode and creates larger coagulation volumes with larger transverse diameters. © 2012 Informa UK Ltd All rights reserved.
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estado: published
related by: authorship_18233
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most specific type: Article
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manufactures: Radionics, United States; Valleylab, United States
related by: authorship_18229
related by: authorship_18232
related by: authorship_18231
type: Document
has publication venue: International Journal of Hyperthermia
date time value: article date 3131
related by: authorship_18228
related by: authorship_18230
related by: authorship_18227
chemicalscas: sodium chloride, 7647-14-5; Saline Solution, Hypertonic
issue: 7
type: Continuant
page end: 662
type: Article
most specific type: Document
pmid: 22974067
type: Generically Dependent Continuant
origen: scopus
page start: 653
has funding vehicle: Ministerio de Ciencia e Innovación, MICINN: TEC2008-01369/TEC, TEC2011-27133-C02-01