Hydrodynamics, mass transfer and rheological studies of gibberellic acid production in an airlift bioreactor
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has funding vehicle: Consejo Nacional de Ciencia y Tecnología, CONACYT: 33973-B, 648-P
page end: 623
abstract: Although a lot of research has been done into modelling microbial processes, the applicability of these concepts to problems specific for bioreactor design and optimization of process conditions is limited. This is partly due to the tendency to separate the two essential factors of bioreactor modelling, i.e. physical transport processes and microbial kinetics. The deficiencies of these models become especially evident in industrial production processes where O2 supply is likely to become the limiting factor, e.g. production of gibberellic acid and other organic acids. Hydrodynamics, mass transfer and rheology of gibberellic acid production by Gibberella fujikuroi in an airlift bioreactor is presented in this work. Important hydrodynamic parameters such as gas holdup, liquid velocity in the riser and in the downcomer, and mixing time were determined and correlated with superficial gas velocity in the riser. Mass transfer was studied evaluating the volumetric mass transfer coefficient, which was determined as a function of superficial gas velocity in the riser and as a function of fermentation time. Culture medium rheology was studied through fermentation time and allowed to explain the volumetric mass transfer coefficient behaviour. Rheological behaviour was explained in terms of changes in the morphology of the fungus. Finally, rheological studies let us obtain correlations for gas holdup and volumetric mass transfer coefficient estimation using the superficial gas velocity in the riser and the culture medium apparent viscosity. © 2006 Springer Science Business Media B.V.
estado: published
type: Thing
type: Document
doi: 10.1007/s11274-006-9270-x
related by: authorship_11024
crisid: 1837
page start: 615
related by: authorship_11023
type: Article
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related by: authorship_11022
related by: authorship_11021
type: Generically Dependent Continuant
related by: authorship_11020
abstract: Although a lot of research has been done into modelling microbial processes, the applicability of these concepts to problems specific for bioreactor design and optimization of process conditions is limited. This is partly due to the tendency to separate the two essential factors of bioreactor modelling, i.e. physical transport processes and microbial kinetics. The deficiencies of these models become especially evident in industrial production processes where O2 supply is likely to become the limiting factor, e.g. production of gibberellic acid and other organic acids. Hydrodynamics, mass transfer and rheology of gibberellic acid production by Gibberella fujikuroi in an airlift bioreactor is presented in this work. Important hydrodynamic parameters such as gas holdup, liquid velocity in the riser and in the downcomer, and mixing time were determined and correlated with superficial gas velocity in the riser. Mass transfer was studied evaluating the volumetric mass transfer coefficient, which was determined as a function of superficial gas velocity in the riser and as a function of fermentation time. Culture medium rheology was studied through fermentation time and allowed to explain the volumetric mass transfer coefficient behaviour. Rheological behaviour was explained in terms of changes in the morphology of the fungus. Finally, rheological studies let us obtain correlations for gas holdup and volumetric mass transfer coefficient estimation using the superficial gas velocity in the riser and the culture medium apparent viscosity. © 2006 Springer Science%2bBusiness Media B.V.
has funding vehicle: 200-C01-77
freetext keyword: Airlift; Gibberellic acid; Hydrodynamics; Mass transfer and rheology Bioreactors; Hydrodynamics; Mass transfer; Mathematical models; Rheology; Viscosity; Airlift; Airlift bioreactor; Gibberellic acids; Physical transport processes; Carboxylic acids; Fungi; Gibberella fujikuroi
origen: scopus
e iscopus: 2-s2.0-34248172387
type: Continuant
has publication venue: World Journal of Microbiology and Biotechnology
issue: 5
volume: 23
most specific type: Article
date time value: article date 1837

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200-C01-77
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funding vehicle for: Hydrodynamics, mass transfer and rheological studies of gibberellic acid production in an airlift bioreactor

Consejo Nacional de Ciencia y Tecnología, CONACYT: 33973-B, 648-P
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funding vehicle for: Hydrodynamics, mass transfer and rheological studies of gibberellic acid production in an airlift bioreactor

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World Journal of Microbiology and Biotechnology
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publication venue for: Hydrodynamics, mass transfer and rheological studies of gibberellic acid production in an airlift bioreactor
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type: Document
type: Generically Dependent Continuant
type: Information Content Entity
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