Document
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58-6250-1-003
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type: BFO_0000020
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type: Thing
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funding vehicle for: Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)

Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)
origen: scopus
type: Thing
related by: authorship_10940
page start: 2381
crisid: 1823
doi: 10.1016/j.febslet.2007.04.035
related by: authorship_10943
abstract: Action of human small intestinal brush border carbohydrate digesting enzymes is thought to involve only final hydrolysis reactions of oligosaccharides to monosaccharides. In vitro starch digestibility assays use fungal amyloglucosidase to provide this function. In this study, recombinant N-terminal subunit enzyme of human small intestinal maltase-glucoamylase (rhMGAM-N) was used to explore digestion of native starches from different botanical sources. The susceptibilities to enzyme hydrolysis varied among the starches. The rate and extent of hydrolysis of amylomaize-5 and amylomaize-7 into glucose were greater than for other starches. Such was not observed with fungal amyloglucosidase or pancreatic α-amylase. The degradation of native starch granules showed a surface furrowed pattern in random, radial, or tree-like arrangements that differed substantially from the erosion patterns of amyloglucosidase or α-amylase. The evidence of raw starch granule degradation with rhMGAM-N indicates that pancreatic α-amylase hydrolysis is not a requirement for native starch digestion in the human small intestine. © 2007 Federation of European Biochemical Societies.
type: Information Content Entity
type: Document
related by: authorship_10939
related by: authorship_10941
freetext keyword: Enzyme; Granule; Human; Maltase-glucoamylase; Small intestine; Starch alpha glucosidase; amylase; amylomaize 5; amylomaize 7; fungal enzyme; glucan 1,4 alpha glucosidase; glucose; recombinant enzyme; starch; unclassified drug; animal cell; article; controlled study; digestion; enzymatic degradation; enzyme subunit; hydrolysis; nonhuman; priority journal; scanning electron microscopy; alpha-Amylase; alpha-Glucosidases; Digestion; Glucan 1,4-alpha-Glucosidase; Humans; Hydrolysis; Intestine, Small; Kinetics; Manihot; Pancreas; Recombinant Proteins; Rhizopus; Starch; Zea mays
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type: Article
type: Generically Dependent Continuant
e iscopus: 2-s2.0-34249276404
most specific type: Document
chemicalscas: alpha glucosidase, 9001-42-7; amylase, 9000-90-2, 9000-92-4, 9001-19-8; glucan 1,4 alpha glucosidase, 9032-08-0; glucose, 50-99-7, 84778-64-3; starch, 9005-25-8, 9005-84-9; Glucan 1,4-alpha-Glucosidase, 3.2.1.3; Recombinant Proteins; Starch, 9005-25-8; alpha-Amylase, 3.2.1.1; alpha-Glucosidases, 3.2.1.20
type: Entity
related by: authorship_10944
has funding vehicle: 58-6250-1-003
accesstype: All Open Access, Bronze
has publication venue: FEBS Letters
pmid: 17485087
has funding vehicle: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF: 3100A0-100772
date time value: article date 1823
issue: 13
page end: 2388
related by: authorship_10938
most specific type: Article
has funding vehicle: Canadian Institutes of Health Research, CIHR: MOP-13338
related by: authorship_10942
estado: published
volume: 581

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RDF description of Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant) - http://orbis.uaslp.mx/vivo/individual/scopus1822
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date: 2026-08-26T23:50:43
publisher: vivo
type: Document

Canadian Institutes of Health Research, CIHR: MOP-13338
type: Relationship
type: BFO_0000020
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type: Thing
type: Grant
type: Continuant
funding vehicle for: Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF: 3100A0-100772
type: Relationship
type: BFO_0000020
type: Entity
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type: Grant
type: Continuant
funding vehicle for: Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)

Article
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Information Content Entity
type: Class

FEBS Letters
type: Collection
type: Document
type: Information Content Entity
type: Periodical
publication venue for: Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)
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type: Thing
type: Journal
type: Entity
type: Generically Dependent Continuant