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Revista Mexicana de Ingenieria Biomedica
Generically Dependent Continuant
Given the price tag of commercially available devices, developing a low-cost, portable pupilometer based on the Raspberry Pi platform is significant for advancing clinical and research applications in neurology and circadian rhythm studies. This study aimed to design and characterize a pupilometer capable of assessing pupillary light response (PLR) to different wavelengths and its relationship with circadian cycles. Using a Raspberry Pi, a no-infrared filter (NoIR) camera, and custom software, the device was tested on a healthy 24-year-old female subject over 20 days, measuring responses to 635 nm (red) and 463 nm (blue) light stimuli at two daily intervals (8:00 AM and 8:00 PM) in both eyes. Results showed that blue light induced greater pupillary constriction than red light (F(1)= 284.37, p=6.9e-27), with more pronounced responses in the morning (F(1)=12.02, p=0.001), likely due to higher parasympathetic activity. Significant lateral asymmetry (F(1)=12.36, p=0.0008) was also observed in the pupillary response to blue light, suggesting potential intracranial factors. These findings demonstrate the pupilometer%27s efficacy in capturing detailed pupillary dynamics, proposing its utility to evaluate pupillary light response in connection with circadian rhythms and lateral asymmetry, providing an affordable solution.
biomedical instrumentation; circadian rhythms; pupillometry
Low-Cost Portable Pupilometer for Circadian Rhythm Studies; [Pupilómetro Portátil de bajo costo para Estudios de Ritmo Circadiano]
RDF description of Low-Cost Portable Pupilometer for Circadian Rhythm Studies; [Pupilómetro Portátil de bajo costo para Estudios de Ritmo Circadiano] - http://orbis.uaslp.mx/vivo/individual/scopus12164