Glucose regulation in type 1 diabetic patients by a multi-doses regimen
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in this paper several multi-doses control regimens are suggested for type 1 diabetic patients. The suggested regimes are proposed based on different insulin formulations. The insulin doses are assumed to be infused by a subcutaneous injection in a three daily regimen prior to each meal. Mixing two types of insulin: rapid or short, and intermediate or long action, the basal and postprandial insulin productions of the pancreas are reproduced. The performance in the glucose regulation is evaluated during a 10-day trial by open-loop and closed-loop simulation with a compartmental model. Copyright © 2005 IFAC.
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Biomedicine; Diabetes; Glucose regulation Insulin; Medical problems; Biomedicine; Closed-loop simulations; Compartmental model; Diabetic patient; Glucose regulation; Open-loop; Glucose
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