Enhanced production of metabolites by elicitation in Opuntia ficus-indica, Opuntia megacantha, and Opuntia streptacantha callus
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Callus from Opuntia streptacantha (cv. Tuna loca), Opuntia megacantha (cv. Rubí reina), and Opuntia ficus-indica (cv. Rojo vigor) were exposed to jasmonic acid (JA) and abiotic stress (drought and UV light) to improve the metabolite production. The callus growth curves, phenolic acids and flavonoids content, antioxidant activity and phenylalanine ammonia lyase (PAL) activity were analyzed under normal and stress conditions. In O. streptacantha callus, the phenolics concentration increased 1.6 to 3 times times in presence of 5%25 PEG or after irradiation with UV light for 240 min, respectively, while flavonoids triplicate with UV light. A significant increase in antioxidant activity was observed in calli from the three Opuntia species in media with 50 µM JA. The relationships between metabolites/PAL activity, and metabolites/antioxidant activity were analyzed using a surface response methodology. Results showed that PAL activity, induced with PEG and UV, correlated with flavonoids content in O. megacantha and O. ficus-indica calli; PAL activity was related to both flavonoids and phenolics compounds in O. ficus-indica and O. megacantha calli exposed to JA, but only to flavonoids in O. streptacantha callus. In general, the JA stimulated simultaneously the metabolic pathways for phenolics and flavonoids synthesis, while abiotic stress induced mainly flavonoids route. As the stressed Opuntia calli exhibited as high antioxidant activity as cladodes, they are a promising system for research on antioxidant biosynthesis and/or to identify new compounds with antioxidant properties. © 2017, Springer Science%2bBusiness Media Dordrecht.
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Flavonoids; Metabolites; Opuntia; Phenolics compounds; Phenylalanine ammonia lyase Amino acids; Ammonia; Antioxidants; Biochemistry; Biomolecules; Metabolites; Plants (botany); Anti-oxidant activities; Antioxidant properties; Metabolite production; Opuntia; Opuntia ficus indica; Phenolics; Phenylalanine ammonia-lyase; Surface response methodologies; Flavonoids; Antioxidants; Flavonoids; Metabolism; Phenol
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