A novel procedure for evaluating gingival perfusion status using laser-Doppler flowmetry
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Objectives: To systematize a procedure that allows one to characterize the perfusion response pattern of attached gingiva to the topical and transitory compression of alveolar mucose, using laser-Doppler flowmetry. Material and methods: A cross-sectional study was carried out, in 20 healthy adult subjects of either sex, with teeth in antero-mandibular sextant but without periodontitis at the lower left lateral incisor (LLLI). Sample was selected by convenience non-probability sampling. Gingival perfusion was evaluated at labial LLLI attached gingiva using a specially designed gingival tray. Two perfusion recordings were carried out 5 min. apart, each one consisting of a 40 s control phase, a 22 s compression phase and a 40 s post-compression phase. During compression phase, LLLI alveolar mucose was compressed with a wood-mounted cotton swab until the perfusion decreased to about 1/5 of its control perfusion value. Results: Integrated primary basal flow (IPBF) during control phase was of 14,210 ± 1075 perfusion units (PU), whereas integrated flow during compression phase was of 1651 ± 202 PU (p < 0.05). After compression was released, integrated total secondary real flow was 13,322 ± 1513 PU (p < 0.05) which represented a 91.3 ± 3.8%25 of IPBF. Gingival compression propitiated an induced flow debt (IFD) of 6478 ± 781 PU, which increased in 980 ± 482 PU after compression was released, representing 18%25 of the IFD (Debt index). Conclusions: A hypoaemic response in reaction to topical and transitory LLLI alveolar mucose compression was observed. Debt index and the ITSRF%25 are reproducible indices of microvascular perfusion response whose validation under pathological circumstances remains to be evaluated. Copyright © Blackwell Munksgaard 2005.
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Gingival perfusion evaluation; Laser-Doppler flowmetry adult; article; blood flow; compression; controlled study; female; gingiva; gingiva; gingivitis; human; hypoxemia; incisor; laser Doppler flowmetry; male; medical assessment; microcirculation; microvascularization; mouth mucosa; pathophysiology; periodontitis; physiology; pressure; prevalence; probability; recording; time; vascularization; Adult; Anoxemia; Cross-Sectional Studies; Female; Gingiva; Gingival Pocket; Gingivitis; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Mouth Mucosa; Pressure; Regional Blood Flow; Time Factors
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