abstract

• ZnO nanoparticles (NPs) were prepared and characterized by different analytical methods and then they were used to decorate with N, N´-bis(salicylidene)ethylenediamine (salen) in order to perform as receptor for the metal ions in an aqueous medium. The results show that ZnO-salen selectively detects Al3 ions in aqueous medium since the intensity of fluorescence has been enhanced significantly. However, the presence of K in the medium further intensified the fluorescence emission for the [ZnO-salen-Al3 ] system. The above system has been applied to recognize Al3 and K in cells by developing the cell images, for which, the fluorescence image is brightened if a human glioblastoma U251 cell contains [ZnO-salen-Al3 ] K ions, consisting of the fluorescence titration. The binding global constant for Al3 and the subsequent recognition of K by ZnO-salen resulted in β2(Al3 ) = 6.61 × 103 and β2(K ) = 3.71 × 103 with a detection limit of 36.51 µM for Al3 and 17.39 µM for K . In the cell toxicity analysis, the cell viability was over 85%25 for the ZnO-salen even in the concentration as high as 100 mM.

authors

• Camacho-Arroyo I.
• Huerta-Aguilar C.A.
• Reyes Domínguez Iván Alejandro
• Thangarasu P.

publication date

• 2024-01-01

funding provided via

• Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México, DGAPA, UNAM, (IN202622); Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México, DGAPA, UNAM  Grant

published in

• Journal of Fluorescence  Journal

keywords

• Aluminium; Chemosensor; Fluorescence; Potassium; ZnO nanoparticles Cell culture; Fluorescence imaging; Titration; Analytical method; Aqueous media; Cell images; Chemo-sensors; Ethylene diamine; Fluorescence emission; Human cells; Metals ions; ZnO; ZnO nanoparticles; ZnO nanoparticles

Digital Object Identifier (DOI)

• 10.1007/s10895-024-03913-4

PubMed ID

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