Synthesis of novel fluorobenzofuroxans by oxidation of anilines and thermal cyclization of arylazides
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The synthesis of several fluorobenzofuroxans by oxidation of fluoroanilines and thermal cyclization of fluoroarylazides is presented. The fluorobenzofuroxans prepared in this study presented tautomerism as evidenced by their NMR data. Benzofuroxans in general have biological activity and are synthetic intermediates for the preparation of several compounds with important pharmaceutical applications. © 2003 Elsevier Science B.V. All rights reserved.
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Fluorobenzofuroxans; Pharmaceuticals; Synthesis aniline derivative; azide; fluorobenzene; furazolidone; article; chemical analysis; controlled study; cyclization; data analysis; nuclear magnetic resonance spectroscopy; oxidation; synthesis; thermal analysis
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