abstract

• Nanocomposites based on graphene oxide (GO) or reduced graphene oxide (rGO) grafted with hollow gold nanoshells (HGNs) were developed as enhanced photothermal agents with improved biocompatibility. Infrared and Raman spectroscopy allowed determining that graphene was highly oxidized due to the presence of oxygenated groups that allowed further functionalization and provided anchor points for the grafting of HGNs. Using HRTEM and STEM, good dispersion of the HGN on the surface of the graphitic materials was observed. Meanwhile, using UV–Vis spectroscopy, an increase of absorbance in the near-infrared region was appreciated, resulting in an enhancement of the photothermal properties of the nanocomposites in contrast to the materials separately. Remarkable temperature increases were obtained in short periods of irradiation using a low-power laser. Moreover, a decrease in the cytotoxicity of GO and rGO was observed in the human neuronal line hNS1 under the presence of the plasmonic nanoparticles on the surface. © The Author(s) 2022.

authors

• González Ortega Omar
• Rodriguez-Montelongo S.A.
• Ruiz Facundo
• Silva Ramírez A.S.

publication date

• 2022-01-01

funding provided via

• 225019, 258444  Grant

published in

• Journal of Composite Materials  Journal

keywords

• Graphene oxide; hollow gold nanoshells; nanocomposites; phototermal therapy; toxicity Biocompatibility; Gold; Gold compounds; Grafting (chemical); Graphene; Infrared devices; Nanoshells; Plasmonics; Anchor point; Functionalizations; Gold nano-shells; Graphene oxide nanocomposites; Graphitic materials; Hollow gold nanoshell; Infrared and Raman spectroscopy; Photo-thermal; Phototermal therapy; Reduced graphene oxides; Nanocomposites

Digital Object Identifier (DOI)

• 10.1177/00219983221073982

PubMed ID

start page

• 1453

end page

• 1464

volume

• 56

issue

• 9