Cytocolposcopic concordance with histopathologic testing in the identification of cervical intraepithelial neoplasia. [Concordancia citocolposcópica con la prueba histopatológica en la identificación de neoplasias intraepiteliales cervicales]
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OBJECTIVE: To evaluate the diagnostic concordance between cytology and colposcopy with respect to the histopathological diagnosis of cervical cancer in women from the state of San Luis Potosí who attended a second-level care hospital. MATERIALS AND METHODS: Correlational study performed in a second-level care hospital in the municipality of San Luis Potosí, between 2015 and 2017. Inclusion criteria: to gather three reports of Papanicolaou, colposcopy and histopathology tests based on Richart%27s classification, to be users of the hospital%27s colposcopy clinic and to have signed the informed consent. To evaluate the diagnostic concordance, taking the histopathological result as a reference, the Kappa test was performed. RESULTS: We studied 379 patients with a mean age of 34.61 years. The sensitivity, specificity, positive and negative predictive value of the Papanicolaou test were: 95.60, 6.60, 96.13 and 5.82%25, respectively. The sensitivity, specificity, positive and negative predictive value of colposcopy were: 95.98, 33.33, 98.90 and 11.76%25, respectively. When doing the Kappa test the outcome for Papanicolaou was: 0.021 (p = 0.677) and for colposcopy 0.154 (p = 0.001). CONCLUSIONS: The sensitivity of the Papanicolaou diagnostic test and colposcopy was high as was the positive predictive value. It is important to analyze the variables that could be causing the diagnostic discordance between Papanicolaou-colposcopy-histopathology. © 2022 Asociacion Mexicana de Ginecologia y Obstetricia. All rights reserved.
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Cervical cancer; Colposcopy; Cytology; Diagnostic concordance; Papanicolaou; San Luis Potosi adult; Article; colposcopy; controlled study; correlational study; cytology; diagnostic test accuracy study; female; histopathology; hospital; human; human tissue; major clinical study; Papanicolaou test; predictive value; sensitivity and specificity; uterine cervix carcinoma in situ
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