abstract

• Nutrition plays a critical role in developmental programs. These effects can be during gametogenesis, gestation, or early life. Omega-3 polyunsaturated fatty acids (PUFA) are essential for normal physiological functioning and for the health of humans and all domestic species. Recent studies have demonstrated the importance of n-3 PUFA in ruminant diets during gestation and its effects on pre-and postnatal offspring growth and health indices. In addition, different types of fatty acids have different metabolic functions, which affects the developmental program differently depending on when they are supplemented. This review provides a broad perspective of the effect of fatty acid supplementation on the developmental program in ruminants, highlighting the areas of a developmental program that are better known and the areas that more research may be needed. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

authors

• Flores-Primo A.
• Lee Rangel Héctor Aarón
• Pinos-Rodríguez J.M.
• Relling A.
• Roque-Jiménez J.A.
• Vicente-Martínez J.G.

publication date

• 2021-01-01

funding provided via

• National Institute of Food and Agriculture, NIFA: 1018667; Ohio State University, OSU; Ohio Agricultural Research and Development Center, Ohio State University, OARDC  Grant

published in

• Animals  Journal

keywords

• Fetal programming; Omega-3; Omega-6; Ruminants ademetionine; arachidonic acid; DNA methyltransferase; docosahexaenoic acid; fatty acid binding protein; fatty acid transporter; ghrelin; glucose; icosapentaenoic acid; linoleic acid; linolenic acid; long chain fatty acid; melanocortin receptor; oleic acid; omega 3 fatty acid; omega 6 fatty acid; ovalbumin; palmitic acid; triacylglycerol; animal welfare; brain development; cattle disease; cognitive development; conception; diet supplementation; DNA damage; DNA methylation; DNA replication; energy metabolism; fetus development; gametogenesis; gene expression; growth, development and aging; lipid metabolism; maternal nutrition; microbial community; neurosecretory cell; nonhuman; oocyte development; primordial germ cell; progeny; Review; skin defect

Digital Object Identifier (DOI)

• 10.3390/ani11030762

PubMed ID

start page

• 1

end page

• 19

volume

• 11

issue

• 3