Genetic analysis of sars‐cov‐2 variants in mexico during the first year of the covid‐19 pandemic
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During the first year of the SARS‐CoV‐2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS‐CoV‐2 lineages and identify the most common circulating lineages during this period. We defined six different geographical regions with particular dynamics of lineage circulation. The Northeast and Northwest regions were the ones that exhibited the highest lineage diversity, while the Central south and South/Southeast regions presented less diversity with predominance of a certain lineage. Addition-ally, by late February 2021, lineage B.1.1.519 represented more than 89%25 of all circulating lineages in the country. © 2021 by the authors. Li-censee MDPI, Basel, Switzerland.
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Genomic surveillance; SARS‐CoV‐2; Viral diversity nonstructural protein 12; open reading frame 3a; open reading frame 7a; open reading frame 7b; open reading frame 8; unclassified drug; viral protein; virus spike protein; adult; aged; Article; controlled study; coronavirus disease 2019; dynamics; epidemiological surveillance; female; gene frequency; gene mutation; gene sequence; genetic analysis; genetic variability; genetic variation; geographic distribution; hospitalization; human; illumina sequencing; major clinical study; male; Mexico; middle aged; nasopharyngeal swab; nucleotide sequence; pandemic; prevalence; quality control; real time polymerase chain reaction; SAR-CoV-2 variant b.1.1.222; SAR-CoV-2 variant B.1.1.519; SARS-Cov-2 variant 501Y.V1; SARS-Cov-2 variant b.1.427; SARS-CoV-2 variant CAL.20C; Severe acute respiratory syndrome coronavirus 2; single nucleotide polymorphism; classification; epidemiology; genetic screening; genetic variation; genetics; molecular evolution; phylogeny; virology; virus genome; whole genome sequencing; COVID-19; Evolution, Molecular; Genetic Testing; Genetic Variation; Genome, Viral; Humans; Mexico; Phylogeny; SARS-CoV-2; Whole Genome Sequencing
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