abstract

• Our work presents a study of the physical phenomena produced in biological-tissue irradiated by pulsed lasers. It is of special interest to us to apply short (Nd:YAG, 5ns) and ultrashort (Ti:Sapphire, 90fs) laser pulses into biological-tissue samples in order to study and understand the interaction features. These laser pulses posses interaction features with tissue that could offer, depending on the pulse parameters, good advantages for medical applications; such features include free heat laser pulse-tissue interaction and excellent mechanical damage confinement. This study was carried out in porcine corneal tissue and biological-tissue models made by agar gel layers combined with organic dye, which allowed us to emulate vascular tissue. The main objective of our study is to understand photo-induced thermal effects and bubble formation in biological-tissue irradiated by short and ultrashort laser pulses. Our results on corneal tissue showed a good potential for novel ophthalmic applications, especially in refractive surgery. In the case of the agar gel biological-tissue models, similar results can be applied in dermatology in order to remove port wine stain or other similar birthmarks.

authors

• Aguilar G.
• Camacho-López S.
• Esparza-Moreno K.P.
• León-Camargo L.
• Mina-rosales A.
• Pérez Gutiérrez Francisco Gerardo
• Romo-Cárdenas G.

publication date

• 2007-01-01

published in

• Proceedings of SPIE - The International Society for Optical Engineering  Proceedings

keywords

• Biological tissue; Corneal tissue; Medical applications; Pulsed laser Bubble formation; Dermatology; Irradiation; Laser surgery; Medical applications; Thermal effects; Tissue; Agar gel layers; Biological tissue; Corneal tissue; Organic dye; Port wine stain; Ultrashort pulses

Digital Object Identifier (DOI)

• 10.1117/12.742272

start page

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volume

• 6422