A bentonitic clay assisted method for the preparation of 2-(R-anilino)-1, 4-naphthoquinones
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A new and efficient protocol to prepare 2-(R-anilino)-1,4-naphthoquinones in quantitative yields is presented. This synthesis occurs under mild conditions by reacting the corresponding aniline and 1,4-naphthoquinone in the presence of a bentonitic clay. The role of the clay is explained in terms of a reaction mechanism in which an activated complex is formed by the reaction of 1,4-naphthoquinone with Lewis acid sites of the clay. Based on the chemical composition of the clay, with Fe3%2b sites, the last step of the mechanism is proposed to involve an oxidationreduction reaction. © Springer Science%2bBusiness Media, LLC 2008.
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