Can nanotechnology help in the fight against COVID-19?
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Overview
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Introduction: The current COVID-19 pandemic caused by the SARS-CoV-2 virus demands the development of strategies not only to detect or inactivate the virus, but to treat it (therapeutically and prophylactically). COVID-19 is not only a critical threat for the population with risk factors, but also generates a dramatic economic impact in terms of morbidity and the overall interruption of economic activities. Areas covered: Advanced materials are the basis of several technologies that could diminish the impact of COVID-19: biosensors might allow early virus detection, nanosized vaccines are powerful agents that could prevent viral infections, and nanosystems with antiviral activity could bind the virus for inactivation or destruction upon application of an external stimulus. Herein all these methods are discussed under the light of cutting-edge technologies and the previously reported prototypes targeting enveloped viruses similar to SARS-CoV-2. This analysis was derived from an extensive scientific literature search (including pubmed) performed on April 2020. Expert opinion: Perspectives on how biosensors, vaccines, and antiviral nanosystems can be implemented to fight COVID-19 are envisioned; identifying the approaches that can be implemented in the short term and those that deserve long term research to cope with respiratory viruses-related pandemics in the future. © 2020 Informa UK Limited, trading as Taylor %26 Francis Group.
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Research
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biosensors; graphene oxide; nanoclays; quantum dots; SARS-CoV-2; silica nanoparticles; silver nanoparticles; virus-like particles multi walled nanotube; nanomaterial; nucleic acid; SARS-CoV-2 vaccine; viral protein; COVID-19 vaccine; nanomaterial; virus vaccine; antibody detection; antigen detection; antiviral activity; coronavirus disease 2019; diagnostic test; diagnostic test accuracy study; DNA hydrogel formation by Isothermal amplification of complementary target; human; infection prevention; microfluidics; Middle East respiratory syndrome coronavirus; nanotechnology; nonhuman; nucleic acid analysis; particle size; protein targeting; Review; SARS-related coronavirus; sensitivity and specificity; serology; Severe acute respiratory syndrome coronavirus 1; Severe acute respiratory syndrome coronavirus 2; surface plasmon resonance; vaccination; virion; virus detection; virus inactivation; virus inhibition; virus like agent; Betacoronavirus; Coronavirus infection; genetic procedures; isolation and purification; nanotechnology; pandemic; physiology; procedures; virus pneumonia; Betacoronavirus; Biosensing Techniques; Coronavirus Infections; Humans; Nanostructures; Nanotechnology; Pandemics; Pneumonia, Viral; Viral Vaccines
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