Therapeutics of neonatal asphyxia in production animals: A review
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The aim of this review is to assess the different treatments and therapeutic protocols used for neonatal asphyxia in animal production. Perinatal asphyxia is considered to be one of the main non-infectious causes of neonatal mortality in the majority of domestic mammals. However, its incidence in intensive animal production is increasing because of a series of implemented strategies aimed at improving and increasing production. For example, through the application of genetics, an increase in size and weight in newly born animals has been achieved. Nevertheless, this has resulted in a larger incidence of dystocia associated with oxygen restriction to the-foetus, which elicits metabolic and respiratory acidosis. Furthermore, aside from immediate financial implications when it comes to production, it also has an impact on the welfare of mother and offspring. Regarding the field of animal perinatology, several therapeutic strategies using respiratory and hormonal stimulants, as well as energetic supplements have been evaluated with the aim of preventing perinatal asphyxia and treating neonates with the condition, and also to diminish the incidence of stillbirths associated with it. However, during the last decades this condition has persisted mainly in porcine, equine, ovine and bovine production; for this reason, it continues to be studied extensively. © 2019 Czech Academy of Agricultural Sciences. All rights reserved.
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Animal perinatology; Calves; Foals; Neonatal mortality; Piglets cocarboxylase; creatine; docosahexaenoic acid; fatty acid; icosapentaenoic acid; linoleic acid; melatonin; methylxanthine; reactive oxygen metabolite; superoxide; animal genetics; animal welfare; Apgar score; asphyxia; blood carbon dioxide tension; brain damage; breathing rate; diet supplementation; domestic animal; dystocia; fetus distress; fetus hypoxia; hypoxia; hypoxic ischemic encephalopathy; incidence; lactation; lipid peroxidation; metabolic acidosis; milk production; newborn; newborn hypoxia; newborn mortality; nonhuman; noninvasive ventilation; oxidative stress; oxygen saturation; perinatal asphyxia; pig; reoxygenation; respiratory acidosis; Review; sheep; stillbirth; uterus contraction; weaning
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