Diabetes and tuberculosis in Mexico: results from epidemiological studies
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The association between tuberculosis (TB) and type 2 diabetes mellitus (DM2) has been recognized during centuries, and recently, a vast number of studies have evidenced their relationship. Uncontrolled diabetes and a poor glycemic control increase the risk for TB infection. Both diseases are considered chronic diseases; constituting important worldwide health problems. In Mexico, the prevalence of DM2 among TB patients varies, rising levels up to 36%25. Several epidemiological studies have been conducted in the country and in the Border States, giving an estimate of the real situation of this comorbidity and in consequence, contributing to improve the diagnosis and follow-up of patients. In this review, we updated the research data on DM2 by means of observational and experimental studies conducted in Mexico in the last 17 years. Results show the continuous increase of TB-DM2 incidence and the need for the establishment of proper control methods acting over this dual axis. © 2018, Research Society for Study of Diabetes in India.
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Comorbidity; Diabetes; Epidemiological studies; Mexico; Tuberculosis advanced glycation end product receptor; cathelicidin antimicrobial peptide LL 37; CD206 antigen; CD64 antigen; chemokine receptor CCR2; lymphocyte membrane receptor; rifampicin; unclassified drug; vitamin D; CD8+ T lymphocyte; cell viability; comorbidity; cytokine response; diabetic patient; disease burden; disease severity; extensively drug resistant tuberculosis; gene expression level; glycemic control; groups by age; human; incidence; infection risk; LL 37 gene; lung alveolus macrophage; lung tuberculosis; Mexico; mononuclear cell; natural killer cell; non insulin dependent diabetes mellitus; nonhuman; outcome assessment; phagocytosis; prevalence; priority journal; protein expression; Review; risk factor; smoking; vitamin blood level
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