abstract

• A new proposal of biocompatible support, Mentha piperita aqueous and ethanolic extract decorated with silver nanoparticles, was successfully proved against C. albicans. Silver nanoparticles (AgNPs) with average size of 20 ± 3 nm, were synthesized to decorate both types of extracts, resulting in variations on the AgNPs distribution on the extract, depending on the solvent nature. The antimycotic activity of ethanolic extract exceeds aqueous extract by 89%25, while decorated supports were 80%25 higher than without AgNPs. The activity of MpExtaq-AgNPs is lower than MpExtet-AgNPs since the nanoparticles are immersed in the extract, avoiding the action against C. albicans, whereas the MpExtet-AgNPs remain on the extract surface. C. albicans optical images showed dismembered cells without hyphae as a result of the treatment with MpExtet-AgNPs. As the MpExtet contains anthocyanins that were not found in MpExtaq, it is concluded that this secondary metabolite must play an important role in antifungal activity. © 2020 Elsevier B.V.

authors

• Cárdenas González Juan Fernando
• Montejano Carrizales Juan Martin
• Patiño-Herrera R.
• Pérez E.
• Pérez Vázquez Francisco Javier
• Robles-Martínez M.

publication date

• 2020-01-01

funding provided via

• Consejo Nacional de Ciencia y Tecnología, CONACYT: CB-2015-252320  Grant

published in

• Colloids and Interface Science Communications  Journal

keywords

• Antimycotic; Candida albicans; Mentha piperita; Secondary metabolites; Silver nanoparticles; Solvent

Digital Object Identifier (DOI)

• 10.1016/j.colcom.2020.100253

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volume

• 35