Prevalence and genotypic characterization of methicillin-resistant strains of staphylococcus aureus isolated in a mexican regional hospital [Prevalencia y caracterización genotípica de cepas de staphylococcus aureus resistente a meticilina aisladas en un hospital regional mexicano] Article uri icon

abstract

  • Background: Staphylococcus aureus is one of most prevalent pathogens in the world associated with a high mortality rate and a rapid development of resistance to antibiotics. Despite its patho-genicity, epidemiological monitoring in Mexico is scarce. Aim: To analyze the local molecular epidemiology and determine the clonal origin of methicillin-resistant (MR) strains isolated from patients admitted to Hospital “Dr. Ignacio Morones Prieto”. Methods: A cross-sectional prospective study was carried out from July to December 2016. The characterization of the strains was carried out by Spa genotyping, frequency of specific virulence genes by PCR and antibiogram. Results: The prevalence of MRSA was 25.7%25, highlighting the presence of the Spa type t895 in 76%25 of the resistant strains and a similar pattern of susceptibility to antibiotics. Conclu-sion: The results of this study indicate that the regional prevalence of MRSA has not changed in the last 10 years and provide valuable information on the clonal origin and the virulence factors of the strains of S. aureus isolated in the region. © 2020, Sociedad Chilena de Infectologia. All rights reserved.

publication date

  • 2020-01-01