Are RA patients from a non-endemic HCV population screened for HCV? A cross-sectional analysis of three different settings [¿Debe de realizarse un tamizaje de VHC en pacientes con artritis reumatoide pertenecientes a un área no-endémica? Estudio transversal en tres diferentes sistemas de salud]
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Introduction In Mexico, other risk factors are associated with hepatitis C virus (HCV): prior heroin users, living alone, widower, and northern region residence. Rheumatoid arthritis (RA) patients are considered immunosuppressed and HCV testing is recommended before treatment. The aim of the study was to describe the characteristics of HCV testing in RA patients in three different medical care settings in a non-endemic area. Methods A retrospective observational study was performed using medical records from 960 RA patients describing the indications for HCV testing. Results The test was performed in 28.6%25 and the HCV overall frequency was 0.36%25. Population characteristics were not associated with an increased risk of HCV infection; therefore, anti-HCV positivity was low. The main reason for testing was before starting biological agents. Conclusion Due to the low pre-test probability, testing for HCV infection should be personalized; i.e., according to disease prevalence in a particular geographical location and the individual risk factors. © 2016 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
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Hepatitis C virus; Rheumatoid arthritis; Risk factors; Testing cyclic citrullinated peptide antibody; disease modifying antirheumatic drug; rheumatoid factor; antirheumatic agent; adult; Article; cross-sectional study; hepatitis C; Hepatitis C virus; human; major clinical study; middle aged; observational study; retrospective study; rheumatoid arthritis; virus diagnosis; aged; clinical practice; complication; female; hepatitis C; immunology; male; Mexico; practice guideline; prevalence; protocol compliance; rheumatoid arthritis; risk factor; statistics and numerical data; virology; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Guideline Adherence; Hepatitis C; Humans; Male; Mexico; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prevalence; Retrospective Studies; Risk Factors
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