abstract

• The aim of this work is to study the behavior of the autonomic system through variations in the heart rate (HR) during the Cyclic Alternating Pattern (CAP) which is formed by A-phases. The analysis was carried out in 10 healthy subjects and 10 patients with Nocturnal Front Lobe Epilepsy (NFLE) that underwent one whole night of polysomnographic recordings. In order to assess the relation of A-phases with the cardiovascular system, two time domain features were computed: the amplitude reduction and time delay of the minimum of the R-R intervals with respect to A-phases onset. In addition, the same process was performed over randomly chosen R-R interval segments during the NREM sleep for baseline comparisons. A non-parametric bootstrap procedure was used to test differences of the kurtosis values of two populations. The results suggest that the onset of the A-phases is correlated with a significant increase of the HR that peaks at around 4s after the A-phase onset, independently of the A-phase subtype and sleep time for both healthy subjects and NFLE patients. Furthermore, the behavior of the reduction in the R-R intervals during the A-phases was significantly different for NFLE patients with respect to control subjects. © 2017 World Scientific Publishing Company.

authors

• Alba Cadena Francisco Alfonso
• Camacho S.
• Dorantes Méndez Guadalupe
• González J.S.
• Luna Rivera José Martin
• Milioli G.
• Méndez García Martin Oswaldo
• Parrino L.
• Riccardi S.
• Terzano M.

publication date

• 2017-01-01

published in

• Fluctuation and Noise Letters  Journal

keywords

• cyclic alternating pattern; heart rate variability; non-parametric analysis; Sleep

Digital Object Identifier (DOI)

• 10.1142/S0219477517500122

start page

end page

volume

• 16

issue

• 2