Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in northern Mexico
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Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%25) patients and 239 (20.1%25) patients had HPV infections; 129 (54.0%25) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%25), 38 (10.6%25), 27 (7.6%25), and 18 (5.0%25) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%25) were clear from HPV infections, 13 (10.1%25) patients had persistent HPV infections, and 12 (9.3%25) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1%25 in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%25) patients had HPV infections. © 2016 International Federation of Gynecology and Obstetrics.
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Cervical cancer; Cytological lesions; HPV; Persistent infection; Risk factors adult; aged; Article; clinical outcome; descriptive research; female; follow up; human; Human papillomavirus type 16; Human papillomavirus type 52; Human papillomavirus type 56; Human papillomavirus type 59; major clinical study; Mexico; middle aged; papillomavirus infection; prevalence; priority journal; prospective study; serotype; sexual behavior; uterine cervix disease; virus infection; Wart virus; adolescent; complication; genetics; isolation and purification; mass screening; Mexico; Papanicolaou test; Papillomaviridae; Papillomavirus Infections; Uterine Cervical Neoplasms; vagina smear; very elderly; virology; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Mass Screening; Mexico; Middle Aged; Papanicolaou Test; Papillomaviridae; Papillomavirus Infections; Prevalence; Prospective Studies; Serogroup; Uterine Cervical Neoplasms; Vaginal Smears; Young Adult
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