Using urinary 1-hydroxypyrene concentrations to evaluate polycyclic aromatic hydrocarbon exposure in women using biomass combustion as main energy source
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Context: The use of solid fuels for cooking and heating is likely to be the largest source of indoor air pollution on a global scale. Objective: The aim of this study was to investigate the urinary excretion of 1-hydroxypyrene (1-OHP) in women living in a rural community, where biomass combustion is used as main energy source during a working day. Materials and methods: The study was performed on urine samples collected in 2012, of 30 healthy women who were residents of a rural community in San Luis Potosi, Mexico. Urine was collected from each woman at three time points (morning, post-lunch and evening) during a working day. The analysis of urinary 1-OHP was performed using high-performance liquid chromatography (HPLC). Also, a health-risk assessment was conducted. Results: The highest levels of 1-OHP in this study were found in the samples taken in the evening (geometric mean ± SD; 0.36 ± 0.13 μg/g creatinine). However, no significant differences among 1-OHP concentrations in the evening and post-lunch samples (0.27 ± 0.10 μg/g creatinine; 0.58 ± 0.67 μg/L) were observed. But, the 1-OHP levels (0.17 ± 0.13 μg/g creatinine; 0.19 ± 0.21 μg/L) found in samples collected in the morning were significantly lower than the 1-OHP levels found in samples collected during post-lunch and evening time. Discussion and conclusion: The data shown in this study demonstrated an increment in the exposure levels to PAHs in women across the shift. However, no health risk was found in this study. © 2014 Informa Healthcare USA, Inc.
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1-Hydroxypyrene; Biomass; Biomonitoring; México; Polycyclic aromatic hydrocarbons; Women 1 hydroxypyrene; creatinine; polycyclic aromatic hydrocarbon; 1-hydroxypyrene; air pollutant; biological marker; polycyclic aromatic hydrocarbon; pyrene derivative; adult; aged; Article; biomass; combustion; creatinine urine level; energy resource; environmental exposure; female; health hazard; high performance liquid chromatography; human; limit of detection; Mexico; normal human; rural population; urinalysis; urinary excretion; urine volume; adverse effects; air pollutant; biotransformation; cooking; environmental monitoring; exposure; health; heating; indoor air pollution; metabolism; middle aged; procedures; risk assessment; time factor; urine; very elderly; women's health; young adult; Adult; Aged; Aged, 80 and over; Air Pollutants; Air Pollution, Indoor; Biomarkers; Biomass; Biotransformation; Chromatography, High Pressure Liquid; Cooking; Environmental Monitoring; Female; Heating; Humans; Inhalation Exposure; Mexico; Middle Aged; Polycyclic Hydrocarbons, Aromatic; Pyrenes; Risk Assessment; Rural Health; Time Factors; Urinalysis; Women's Health; Young Adult
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