abstract

• Background: Publishing negative seroprevalence studies not only helps to have more accurate seroprevalence estimates but also allows calculating the specificity of the diagnostic tests used. We performed a population-based Trypanosoma cruzi seroprevalence survey in a community in central Mexico. Results: We surveyed 204 women and children and collected blood by finger prick. We performed rapid tests (Stat-Pak, Chembio, Inc., Medford, New York) and recombinant Chagas ELISA tests v3.0 (Wiener, Rosario, Argentina). All rapid tests and all ELISA tests were negative. Conclusion: The rapid test had 100 %25 of specificity compared to the ELISA. © 2015 Padilla-Raygoza et al.

authors

• Buekens P.
• Diaz-Guerrero R.
• Dumonteil E.
• Gamboa León Miriam Rubí de los Milagros
• Padilla-Raygoza N.
• Ramirez-Sierra M.J.
• Ruiz-Paloalto M.L.

publication date

• 2015-01-01

published in

• BMC Research Notes  Journal

keywords

• Antibodies; Specificity; Trypanosoma cruzi protozoon antibody; adolescent; adult; blood; Chagas disease; child; diagnostic test; enzyme linked immunosorbent assay; female; human; immunology; Mexico; middle aged; parasitology; pregnancy; preschool child; sensitivity and specificity; standards; Trypanosoma cruzi; Adolescent; Adult; Antibodies, Protozoan; Chagas Disease; Child; Child, Preschool; Diagnostic Tests, Routine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Mexico; Middle Aged; Pregnancy; Sensitivity and Specificity; Seroepidemiologic Studies; Trypanosoma cruzi

Digital Object Identifier (DOI)

• 10.1186/s13104-015-1612-z

PubMed ID

• 26510987

start page

end page

volume

• 8

issue

• 1