Concentrations of persistent organic pollutants (POPs) in human blood samples from Mexico City, Mexico
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Studies in Mexico have demonstrated exposure to persistent organic pollutants (POPs) in people living in different sites through the country. However, studies evaluating exposure to POPs in people living in Mexico City (one of most contaminated places in the world) are scarce. Therefore, the aim of this study was to assess the levels of polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite dichlorodiphenyldichloroethylene (DDE) in the blood as exposure biomarkers in people living in Mexico City. A total of 123 participants (blood donors aged 20-60. years) were recruited during 2010 in Mexico City. Quantitative analyses of blood samples were performed using gas chromatography coupled with mass spectrometry. Levels of the assessed compounds ranged from non-detectable (< LOD) to 350. ng/g lipid; from 8.20 to 91.0. ng/g lipid and from < LOD to 34.0. ng/g lipid for total PBDEs, total PCBs and total DDT, respectively. The current study indicates POP exposure in the people assessed and highlights the need for further biomonitoring studies of these POPs in the region. In this regard, biomonitoring of toxins on a global scale may be the first step towards the prevention of toxin-induced illnesses in the population. © 2013 Elsevier B.V.
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Biomonitoring; Mexico; P,p'-DDE; PBDEs; PCBs; POPs Blood; Gas chromatography; Mass spectrometry; Metabolites; Polychlorinated biphenyls; Biomonitoring; Me-xico; P ,p' ddes; PBDEs; PCBs; POPs; Organic pollutants; 1,1 dichloro 2,2 bis(4 chlorophenyl)ethylene; 2,2',4,4',5,5' hexabromodiphenyl ether; brominated diphenyl ether 100; brominated diphenyl ether 154; brominated diphenyl ether 47; brominated diphenyl ether 99; chlorphenotane; environmental, industrial and domestic chemicals; ether derivative; persistent organic pollutant; polybrominated diphenyl ether; polychlorinated biphenyl 105; polychlorinated biphenyl 118; polychlorinated biphenyl 128; polychlorinated biphenyl 138; polychlorinated biphenyl 153; polychlorinated biphenyl 156; polychlorinated biphenyl 170; polychlorinated biphenyl 180; polychlorinated biphenyl 183; polychlorinated biphenyl 187; polychlorinated biphenyl 28; polychlorinated biphenyl 52; polychlorinated biphenyl 99; polychlorinated biphenyl derivative; unclassified drug; biomarker; biomonitoring; blood; concentration (composition); DDE; DDT; gas chromatography; lipid; metabolite; organic pollutant; PBDE; PCB; adult; article; biological monitoring; blood analysis; blood donor; blood level; blood sampling; controlled study; environmental exposure; female; human; limit of detection; male; mass fragmentography; Mexico; pollution; preventive medicine; priority journal; quantitative analysis; Federal District [Mexico]; Mexico City; Mexico [North America]; Biomonitoring; Mexico; p,p′-DDE; PBDEs; PCBs; POPs; Adult; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; Environmental Pollutants; Female; Halogenated Diphenyl Ethers; Humans; Hydrocarbons, Chlorinated; Male; Mexico; Middle Aged; Polychlorinated Biphenyls; Young Adult
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