Effect of an immunization program on seasonal influenza hospitalizations in Mexican children
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We analyzed 2378 respiratory samples of children <5 years of age admitted during a 7-year period in order to determine the contribution of seasonal influenza as a cause of hospitalizations, as well as the impact of the inclusion of influenza vaccine in the childhood immunization program. The presence of influenza virus was demonstrated in 106 (4.4%25) samples. The proportion of influenza hospitalizations after the introduction of influenza vaccination was lower (3.4%25) than before the establishment of this vaccination program (7.5%25; P = 0.00002). Our study shows that influenza vaccination programs in children significantly reduce the impact of influenza related hospitalizations. © 2010 Elsevier Ltd. All rights reserved.
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Immunization; Influenza; Influenza vaccine; Mexico; Respiratory infections influenza vaccine; article; child; female; hospitalization; human; infant; influenza; influenza vaccination; major clinical study; male; Mexico; newborn; outcome assessment; preschool child; preventive health service; priority journal; school child
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