Kinetic study of the adsorption of nitroimidazole antibiotics on activated carbons in aqueous phase

The adsorption kinetics of four nitroimidazoles, Dimetridazole (DMZ), Metronidazole (MNZ), Ronidazole (RNZ) and Tinidazole (TNZ), were studied on three activated carbons: two commercial carbons from Sorbo-Norit (S) and Merck (M) and a third prepared by chemical activation of petroleum coke (C). Experimental data of the corresponding adsorption kinetics were analyzed by applying pseudo-first and pseudo-second-order models and a general diffusion model. Application of pseudo-first and pseudo-second-order kinetic models verified the following: (i) The kinetic model used that better predicts the adsorption rates depends of both the adsorbent and adsorbate studied. (ii) Nitroimidazole adsorption rate decreases in the order MNZ>DMZ>RNZ>TNZ; therefore, in the case of MNZ, molecular size does not appear to be a determining factor in the process. (iii) Nitroimidazole adsorption rate on carbons increases in the order C

Activated carbon; Adsorption kinetics; Intraparticle diffusion; Nitroimidazoles Activated carbon adsorption; Adsorption kinetics; Adsorption mechanism; Adsorption process; Adsorption rates; Aqueous phase; Chemical characteristic; Diffusion model; Diffusivities; Dimetridazole; Experimental data; Hydrophobic interactions; Intra-particle diffusion; Kinetic models; Kinetic study; Mass transport; Metronidazole; Molecular size; Nitroimidazoles; Pseudo-second order model; Pseudo-second-order kinetic models; Textural parameters; Adsorbates; Adsorption; Chemical activation; Diffusion; Drug products; Hydrophobicity; Kinetic theory; Petroleum coke; Sewage treatment plants; Surface structure; Activated carbon; activated carbon; adsorbent; antibiotic agent; carbon; coke; dimetridazole; metronidazole; nitroimidazole; petroleum; ronidazole; tinidazole; adsorption; adsorption kinetics; article; controlled study; diffusion; drug structure; hydrophobicity; mathematical model; molecular size; prediction; priority journal; Adsorption; Anti-Bacterial Agents; Charcoal; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Chemical; Nitroimidazoles

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