abstract

• To produce patterns of porous polystyrene films that can be used as standards to be compared with cancer cell patterns, thin films were made by dissolving polystyrene (PS) and polybutylmethacrylate (PBMA) in tetrahydrofuran, then PBMA phase was removed using acetic acid (AA) to generate rough surfaces. The mixture of %25PS/%25PBMA was formed from the following weight ratios 1/99, 5/95,…, 90/10, 99/1. The highest water contact angle (WCA) for 40/60 porous polystyrene film was (139.4 ± 1°), exceeding the WCA of the film before removing the PBMA by 95.2 ± 0.2°; at the same concentration, the film roughness increases 80%25 by removing the PBMA. The topography of porous polystyrene films is similar to that of cancer cells and the fractal dimension (Df) of the 20/80, 30/70, 35/65, 38/62, 40/60, 43/57, 45/55, and 50/50 porous polystyrene films range between 1.6 and 2, which agrees with those reported in the literature for cancerous structures. Thus, Df data and polystyrene film topography with different porosity degrees can be used as patterns in digital recognition techniques for cancer diagnosis. © 2022 Society of Plastics Engineers.

authors

• García-Hernández E.
• Patiño-Herrera R.
• Pérez E.

publication date

• 2022-01-01

funding provided via

• Tecnológico Nacional de México, TNM: 11186.21‐PD, 11383.21‐PD, 14439.22‐PD  Grant

published in

• Polymer Engineering and Science  Journal

keywords

• Fractal dimension; Mixture of immiscible polymers; Pattern recognition; Porous polystyrene; Topography images Cancer cells; Cells; Contact angle; Diseases; Mixtures; Pattern recognition; Polystyrenes; Thin films; Topography; Cancer cells; Cell patterns; Fractal dimension analysis; Immiscible polymer; Mixture of immiscible polymer; Polybutylmethacrylate; Polystyrene films; Porous polystyrene; Topography images; Water contacts; Fractal dimension

Digital Object Identifier (DOI)

• 10.1002/pen.26101

PubMed ID

start page

• 3269

end page

• 3278

volume

• 62

issue

• 10