National Institutes of Health, NIH; National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIAMS: P30 AR070253, P30 AR072577, R01 AR077607; Amgen; Bristol-Myers Squibb, BMS; Eli Lilly and Company; Pfizer; Novartis; Sanofi; Gilead Sciences; Rheumatology Research Foundation, RRF; Meso Scale Diagnostics, MSD; Janssen Pharmaceuticals; School of Public Health, University of California Berkeley, UCB; Manchester Biomedical Research Centre, BRC; UCB Pharma: K24 AR074534, P30 AR070155; National Institute for Health and Care Research, NIHR; UCLH Biomedical Research Centre, NIHR BRC Grant